Wanqiu Chen Selected Research

N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone

3/2010	Ac-YVAD-CMK Decreases Blood-Brain Barrier Degradation by Inhibiting Caspase-1 Activation of Interleukin-1β in Intracerebral Hemorrhage Mouse Model.
12/2009	Caspase-1 inhibitor prevents neurogenic pulmonary edema after subarachnoid hemorrhage in mice.

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Wanqiu Chen Research Topics

Disease

13	Brain Injuries (Brain Injury) 01/2012 - 08/2007
12	Brain Edema (Cerebral Edema) 01/2012 - 08/2007
9	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 01/2011 - 03/2008
5	Inflammation (Inflammations) 01/2012 - 02/2010
5	Hypoxia (Hypoxemia) 03/2011 - 09/2008
4	Hereditary Hemorrhagic Telangiectasia 01/2018 - 06/2011
4	Ischemia 03/2011 - 11/2009
4	Herpes Zoster 01/2011 - 12/2009
3	Arteriovenous Malformations (Arteriovenous Malformation) 01/2018 - 02/2013
3	Intracranial Vasospasm 01/2011 - 12/2008
2	Breast Neoplasms (Breast Cancer) 01/2021 - 01/2021
2	Osteoporosis 06/2020 - 07/2015
2	Hemorrhage 01/2018 - 01/2012
2	Atrophy 03/2010 - 11/2009
2	Cerebral Hemorrhage 03/2010 - 03/2010
2	Body Weight (Weight, Body) 02/2010 - 11/2009
1	Neoplasms (Cancer) 01/2021
1	Aneuploidy (Aneuploid) 01/2021
1	Hematologic Neoplasms (Hematological Malignancy) 01/2020
1	Hemophilia A (Haemophilia) 12/2019
1	Vascular Malformations 01/2018
1	Osteomalacia 07/2015
1	Secondary Hyperparathyroidism 07/2015
1	Bone Fractures (Bone Fracture) 07/2015
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 07/2015
1	Neuroinflammatory Diseases 01/2012
1	Rupture 06/2011
1	Muscle Spasticity (Spastic) 11/2010
1	Hemorrhagic Stroke 03/2010
1	Brain Ischemia (Cerebral Ischemia) 01/2010

Drug/Important Bio-Agent (IBA)

6	Matrix Metalloproteinases (MMPs)IBA 01/2011 - 11/2009
5	OsteopontinIBA 03/2011 - 02/2010
4	Tight Junction ProteinsIBA 01/2011 - 11/2009
4	Oxygen (Dioxygen)IBA 01/2011 - 03/2009
3	Proto-Oncogene Proteins c-sis (Platelet Derived Growth Factor B)IBA 06/2020 - 07/2015
3	Proteins (Proteins, Gene)FDA Link 06/2020 - 02/2010
3	Activin Receptors (Activin Receptor)IBA 03/2014 - 06/2011
3	Matrix Metalloproteinase 9 (Gelatinase B)IBA 03/2010 - 01/2010
2	Neuroprotective AgentsIBA 05/2011 - 03/2010
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2011 - 12/2008
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2011 - 12/2008
2	Laminin (Merosin)IBA 01/2011 - 02/2010
2	N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketoneIBA 03/2010 - 12/2009
2	MelatoninIBA 03/2010 - 03/2008
2	interleukin-1beta-converting enzyme inhibitorIBA 03/2010 - 12/2009
2	salicylhydroxamic acid (SHAM)IBA 02/2010 - 01/2010
1	Small Cytoplasmic RNAIBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	antineoplaston A10 (A 10)IBA 12/2019
1	7,7'- dimethoxy- (4,4'- bi- 1,3- benzodioxole)- 5,5'- dicarboxylic acid dimethyl ester (BDD)IBA 12/2019
1	Thalidomide (Thalomid)FDA Link 01/2018
1	Lenalidomide (CC 5013)FDA Link 01/2018
1	Becaplermin (PDGF-BB)FDA Link 07/2015
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 07/2015
1	Phosphoglycerate Kinase (Kinase, Phosphoglycerate)IBA 07/2015
1	EndoglinIBA 01/2014
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2013
1	InterleukinsIBA 01/2012
1	Myelin Basic ProteinIBA 01/2012
1	CytokinesIBA 01/2012
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2012
1	AntigensIBA 01/2012
1	HydrogenIBA 05/2011
1	P-SelectinIBA 03/2011
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2011
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 03/2011
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 03/2011
1	3-fluoro-2-(4-methoxybenzyl)allylamineIBA 03/2011
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2011
1	Mitogen-Activated Protein KinasesIBA 01/2011
1	Endothelin Receptors (Endothelin Receptor)IBA 01/2011
1	Extracellular Matrix ProteinsIBA 01/2011
1	Calmodulin-Binding Proteins (Caldesmon)IBA 11/2010
1	Aspartic Acid (Aspartate)FDA Link 11/2010
1	IntegrinsIBA 11/2010
1	HSP27 Heat-Shock ProteinsIBA 11/2010
1	Free RadicalsIBA 03/2010
1	AntioxidantsIBA 03/2010
1	Free Radical ScavengersIBA 03/2010
1	CarbenoxoloneIBA 02/2010
1	Metalloproteases (Metalloproteinases)IBA 02/2010
1	Glycoproteins (Glycoprotein)IBA 02/2010
1	AlbuminsIBA 02/2010
1	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 02/2010
1	NF-kappa B (NF-kB)IBA 02/2010
1	alanylaspartic acidIBA 12/2009
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 12/2009
1	Peroxidase (Myeloperoxidase)IBA 12/2009
1	Pharmaceutical PreparationsIBA 12/2009
1	Interleukin-18 (Interleukin 18)IBA 12/2009
1	KetonesIBA 12/2009
1	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketoneIBA 12/2009
1	Caspase 3 (Caspase-3)IBA 12/2009

Therapy/Procedure

3	Ligation 03/2011 - 09/2008
2	Transplantation 01/2020 - 07/2015
2	Therapeutics 07/2015 - 06/2011
1	Electrocoagulation (Electrocautery) 01/2012
1	Operative Surgical Procedures 05/2011
1	Hyperbaric Oxygenation 01/2011
1	Neurosurgical Procedures 01/2011